I installed the stable 1.4.6 version last night on a mac (10.12). Got past the gate-keeper, no issues. I did not install Ghostscript.
I then generated a quick test page, shared it with my printer, he's good with the bleeds, resolution, etc. So that's all promising!
My questions are around fonts ... I know that there are a lot more fonts available on other programs I run on my Mac than what I see in Scribus. Does Scribus only recognize existing TT fonts? Does it only include those that came in the install package? Most of what's available out of the box looks to be fairly "plain," and I'm looking for a fairly "clean" (not overly fancy) calligraphic font.
Also, I don't see any sort of font "preview" until I've already used it in the text box. I guess that's OK if I know ahead of time what font I'm looking for, but it seems rather odd. Maybe I missed something (ghostscript?) that would remedy that.
Not sure if I have to find/downlaod/install something, or if Scribus can use other fonts that are already residing "somewhere" on my Mac. For clarification, I've never intentionally installed a font on this Mac, anything currently on it either came with the OS or one of few Apps I've installed.